hyperpathia
Conditions
Interventions
Groups A:Normal saline (1 g/kg) was pumped within 10min before induction of anesthesia, followed by continuous pumping (0.5 g/kg/h) until 30min before the end of surgery. Dezocine was administrated or
Groups B:DEX (1 g/kg) was pumped within 10min before induction of anesthesia, and 0.5 g/kg/h was continuously pumped until 30min before the end of surgery. The same volume of normal saline was injecte
Groups AB:DEX (1 g/kg) was pumped within 10min before induction of anesthesia, 0.5 g/kg/h was continuously pumped after completion until 30min before the end of surgery, and dezocine was administrated
Groups C:Normal saline (1 g/kg) was pumped within 10min before induction of anesthesia, and continued to be pumped (0.5 g/kg/h) until 30min before the end of surgery. The same volume of normal saline
Sponsors
Department of Anesthesiology, Second Affiliated Hospital of Xi'an Jiaotong University
Eligibility
Sex/Gender
Female
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients admitted to our hospital for gynecological laparoscopic surgery under general anesthesia; 2. ASA grade I-II; 3. Aged 20-60 years; 4. BMI 18-29 kg/m2; 5. Operation time is more than 1 hour; 6. Patients or their family members sign informed consent forms.
Exclusion criteria
Exclusion criteria: 1. Patients who are allergic to the test drugs or have other contraindications; 2. Serious diseases of the heart, brain, liver, kidney, lung and endocrine system; 3. A history of mental disorder, chronic pain or pain paresthesia; 4. A recent history of pain including surgery and trauma; 5. Patients who take sedatives and analgesics for a long time or rely on sedatives and analgesics; 6. Alcoholism patients; 7. Patients with cognitive dysfunction; 8. Pregnant and lactating women; 9. Participated in additional clinical studies in the past 30 days.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain threshold; | — |
Secondary
| Measure | Time frame |
|---|---|
| NRS score, Ramsay score, BCS score;Postoperative analgesic drug addition, postoperative analgesic pump effective times; | — |
Countries
China
Contacts
Public ContactZhang Pengbo
The Second Affiliated Hospital of Xi'an Jiaotong University
Outcome results
None listed