general anesthesia
Conditions
Interventions
1.0 mg/kg succinylcholine group, 1.5 mg/kg succinylcholine group and 1.2 mg/kg rocuronium group :Nil
Sponsors
Shanghai General Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: ASA physical status I-II, aged 18-65 years, scheduled for selective surgery, sign the infomed consent.
Exclusion criteria
Exclusion criteria: 1. Pregnancy; 2. Difficult intubation history; 3. Obstructive sleep apnea syndrome; 4. Respiratory infection in recent 1 month; 5. Quit smoking less than two months before operation; 6. Have a history of alcohol or drug abuse; 7. Cerebrovascular diseases and increased intracranial pressure; 8. Administration of drugs that can attenuate rocuronium (such as phenytoin sodium, carbamazepine or protease inhibitors).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Apnea durationin;Tracheal intubation conditions;Classification of laryngoscope exposure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fibrillation time;Classification of muscle fibrillation degree;Heart rate;Blood pressure;ETO2;PETCO2;SpO2;Nasopharynx temperature;BIS;Arterial blood gas analysis;Adverse event; | — |
Countries
China
Contacts
Public ContactLijun Tang
Department of Anesthesiology, Shanghai General Hospital
Outcome results
None listed