erosive oral lichen planus
Conditions
Interventions
experimental group:intralesional i-PRF injection, another intralesional injectiom a week later if the lesion not healed
controlled group:intralesional triamcinolone acetonide injection, another intralesional injectiom a week later if the lesion not healed
Sponsors
Hospital of Stomatology Affiliated to Nanchang University
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. A subject diagnosed as an erosive oral lichen planus based on medical history, clinical manifestations, and/or pathological findings; Who aged >=18 years old, and the relevant treatment is not taken for this disease; 2. The age of onset is 18 to 60 years old, and the relevant treatment is not taken for this disease; 3. Lesion area<=3cm2; 4. No blood system disease; 5. Patients who agree and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. Conmbined with other identified oral mucosal diseases; 2. The location of erosion is not conducive to observation and measurement; 3. Histological signs of dysplasia; 4. Certain drugs or amalgam fillings may cause mossy-like reactions; 5. Those who have used antibiotics within 3.1 months and have used immunologic preparations within 3 months; 6. Pregnant women, lactating women; 7. Allergies and a history of allergies to drugs and food; 8. Patients with systemic diseases such as autoimmune related diseases, diabetes, hepatitis C and tumor that seriously affect lichen planus; 9. Those who do not follow medical advice or are unable to return on time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The degree of pain (Visual Analogue Scale, VAS); | — |
Secondary
| Measure | Time frame |
|---|---|
| erosive lesion area; | — |
Countries
China
Contacts
Public ContactJuanjuan Zong
Hospital of Stomatology Affiliated to Nanchang University
Outcome results
None listed