Nonalcoholic fatty liver disease,NAFLD
Conditions
Interventions
experimental group:intervention group will receive LBP supplementation capsule
control group:control group will receive an identical appearance capsule containing maltodextrin as the placebo
Sponsors
Ningxia Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: All NAFLD patients who were treated in the General Hospital of Ningxia Medical University were recruited and invited to participate. The specific inclusion criteria were as follows: 1. Subjects with abnormal liver enzymes and NAFLD diagnosed by ultrasound; 2. Patients aged 45-59 years; 3. Patients who are willing to participate in the study and sign informed consent.
Exclusion criteria
Exclusion criteria: 1. In the past six months, men who drink more than 140g / week and women who drink more than 70g / week; 2. Patients with a history of acute or chronic viral hepatitis, drug-induced liver disease or autoimmune hepatitis; 3. Patients with inflammatory bowel disease or other chronic inflammation; 4. Patients with diabetes, uncontrolled hypertension, chronic kidney disease, hyperthyroidism, myocardial infarction or heart failure within 6 months; 5. Patients who are taking other drugs, such as probiotic supplements and foods, immunosuppressants, antibiotics, corticosteroid drugs, valproic acid and amiodarone.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| ALT concentration relief; | — |
Secondary
| Measure | Time frame |
|---|---|
| body composition evaluated;Gut microbiota abundance and diversity;Intestinal permeability;Patient's characteristics demographic data;haematological index;Ultrasonography;Physical-activity;Compliance and adverse reactions; | — |
Countries
China
Contacts
Public ContactYang Jianjun
Ningxia Medical University
Outcome results
None listed