Non-organic insomnia
Conditions
Interventions
Trazodone treatment group:trazodone
Mirtazapine treatment group:Mirtazapine
Fluvoxamine treatment group:Fluvoxamine
CBTI combined with hypnotic therapy group:CBTI combined with hypnotic therapy
Agomelatine treatment group:Agomelatine
Sponsors
The Second Affiliated Hospital of Xinxiang Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 68 Years
Inclusion criteria
Inclusion criteria: 1. Subjects aged over 18 years old; 2. Those who have been educated for more than 5 years (including 5 years); 3. Those who meet the diagnostic criteria of ICD-10 for non organic insomnia.
Exclusion criteria
Exclusion criteria: 1. Patients with major psychological stress not yet solved or undergoing other psychotherapy at the time of enrollment; 2. Patients with a history of schizophrenia or other serious psychiatric disorders; 3. Patients who have been abusing alcohol and drugs for more than 10 years; 4. Subjects who use any psychoactive substances or drink more than four standard cups of wine every day three days before the test; 5. Patients with severe somatic disease, somatic disease or acute phase of any disease; 6. Patients with mental retardation or extensive developmental disorders.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hcy;Neuropsychological cognitive assessment;fMRI;Genes associated with impaired cognitive function in patients with insomnia; | — |
Countries
China
Contacts
Public ContactXu Yahui
The Second Affiliated Hospital of Xinxiang Medical College
Outcome results
None listed