Effect of ozone therapy on clinical and imaging outcomes in patients with femoral head osteonecrosis: a randomized controlled trial.

Comparative study on the effect of ozone therapy and core decompression in patients with femoral head necrosis

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000034733

Enrollment

Unknown

Registered

2020-07-16

Start date

2020-12-01

Completion date

Unknown

Last updated

2020-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Osteonecrosis of the femoral head

Interventions

Ozone therapy:ozone hip injection

core decompression :core decompression surgery

Eligibility

Sex/Gender

All

Age

18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-70 years; 2. Patients with ARCO I-III femoral head necrosis; 3. Voluntarily participate in this study and sign an informed consent form.

Exclusion criteria

Exclusion criteria: 1. Severe heart, brain, liver and kidney diseases; 2. Complications of large blood vessels, such as stroke with limb disorders; 3. Pregnant women and lactating women; 4. Those who are contraindicated by interventional treatment with ozone therapy. 5. Those who are contraindicated in core decompression surgery.

Design outcomes

Primary

Measure	Time frame
Visual analog scale;Harris hip score;	—

Secondary

Measure	Time frame
bone marrow edema;size of the lesion;	—

Countries

China

Contacts

Public ContactJianxiong An

Department of Anesthesiology, Pain Medicine & Sleep Medicine, Aviation General Hospital of Medical University

anjianxiong@yeah.net+86 010-59520288

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026