Skip to content

Progestogen pre-treatment in IVF using an antagonist protocol: a randomized controlled non-inferiority trial

Progestogen pre-treatment in IVF using an antagonist protocol: a randomized controlled non-inferiority trial

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000034731
Enrollment
Unknown
Registered
2020-07-16
Start date
2020-08-01
Completion date
Unknown
Last updated
2020-08-10

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Infertility

Interventions

experimental group:take Duphaston 10mg b.d. from day 21 for 7-10 day
control group:nil

Sponsors

Reproductive Medicine Department of the University of Hong Kong-Shen Zhen Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Age of women <43 years; 2. BMI <30Kg/m2; 3. Infertile women undergoing IVF using antagonist protocol; 4. Not receiving other hormonal therapy or participating other RCT research.

Exclusion criteria

Exclusion criteria: 1. Presence of a functional ovarian cyst with E2>100 pg/mL. 2. Taking any other hormonal preparation. 3. Recipient of oocyte donation. 4. Undergoing preimplantation genetic testing 5. Presence of hydrosalpinx which is not surgically treated or endometrial polyp on scanning during ovarian stimulation.

Design outcomes

Primary

MeasureTime frame
the live birth rate per the first transfer (fresh or frozen).;

Secondary

MeasureTime frame
pregnancy test positive per the first transfer (fresh or frozen);clinical pregnancy per the first transfer (fresh or frozen);ongoing pregnancy per the first transfer (fresh or frozen);Number of follicles >14mm and >16mm on day of hCG/agonist trigger;Number of eggs aspirated/fertilized/cleaved;Serum Estradiol /P level after 7 days of FSH and on the day of hCG /agonist trigger;

Countries

China

Contacts

Public ContactWang Xiaohui

The University of Hong Kong-Shenzhen Hospital

wangxh@hku-szh.org+86 13922854346

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026