An randomized controlled study on xerostomia induced by fluorouracil chemotherapy in patients with gastrointestinal tumors

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000034729

Enrollment

Unknown

Registered

2020-07-16

Start date

2020-08-01

Completion date

Unknown

Last updated

2020-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

xerostomia caused by chemotherapy

Interventions

dark plum juice group:dark plum juice group

mint and lemon juice group:mint and lemon juice group

Control Group:none

Eligibility

Sex/Gender

All

Inclusion criteria

Inclusion criteria: 1.Pathological diagnosis of digestive tract tumors. 2.Patients were treated with fluorouracil and the survival time was more than 6 months. 3.Tolerate the taste of plum, licorice and lemon, and have no allergy or adverse reactions.Patients' informed consent to participate in this study.

Exclusion criteria

Exclusion criteria: 1. Patients with stomatitis or xerostomia before chemotherapy. 2. Complicated with cardiovascular, liver, kidney and hematopoietic system and other serious primary diseases as well as diabetes and depression, psychiatric patients. 3. Cannot gargle through the mouth. 4. Recent history of diseases and medication that affect salivary gland function.

Design outcomes

Primary

Measure	Time frame
unstimulated whole saliva;Linear visual simulation scoring;EORTC QLQ—C30;	—

Countries

China

Contacts

Public ContactChen Zhuoyan

Department of Medical Oncology, Fujian Cancer Hospital & Fujian Medical University Cancer Hospital

304909247@qq.com+86 15959084182

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026