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Effect of multi-modal perception feedback training on upper limb function and brain plasticity in stroke patients: a randomized controlled trial.

Effect of multi-modal perception feedback training on upper limb function and brain plasticity in stroke patients

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000034725
Enrollment
Unknown
Registered
2020-07-16
Start date
2020-08-01
Completion date
Unknown
Last updated
2020-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

experiment group:multi-modal perception feedback training
control group:classic motor imagery therapy

Sponsors

Huashan Hospital, Fudan University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Willing to sign informed consent; 2. Age between 20 to 75 years old, male or female; 3. Diagnosis in accordance with the key criteria point rasied in 1995 conference; 4. Confirmed by CT or MRI of the brain; 5. Paretic wrist motor impairment, no active wrist motion and strength between 0-1; 6. Disease duration above 6 months; 7. Vital signs stable.

Exclusion criteria

Exclusion criteria: 1. Cognitive impairment assessed by MMSE; 2. Auditory or vision impairment; 3. The questionnaire survey on motor and visual imagery shows that motor imagery cannot be performed; 4. Those with severe cardiopulmonary, liver, and kidney dysfunction who are not suitable for rehabilitation training (in the past 6 months, due to any cause of congestive heart failure (CHF) attack or worsening. Any need to change the dosing regimen, diet or hospitalization Heart failure is the onset of CHF; known valvular heart disease with CHF; thoracotomy cardiac surgery (eg, coronary artery bypass, valve replacement); acute myocardial infarction in the past 3 months; acute urgency on admission Signs or symptoms of infarction, including electrocardiographic findings; suspected aortic dissection on admission; acute arrhythmia with hemodynamic instability (including any tachycardia or bradycardia), etc.; liver dysfunction (Gu Bing, Asparagus is more than 1.2 times the normal range); blood creatinine and urea nitrogen are more than 1.2 times the normal range; existing acute or chronic lung disease); poor blood pressure and blood glucose control, blood pressure is detected as systolic blood pressure >= 140mmHg, diastolic blood pressure >= 90mmHg; 5. Patients with metal in the body (pacemaker, arterial stent, etc.), cannot complete MRI examination; 6. Pregnant or lactating women; 7. Poor compliance and unable to complete this training; 8. Those who participated in other clinical trials at the same time.

Design outcomes

Primary

MeasureTime frame
AROM of paretic wrist;

Secondary

MeasureTime frame
Brunnstrom (upper limb and hand);ARAT;Fugl Meyer for upper limb;Key muscle strength of upper limb;Key muscle tension of upper limb;ADL;EEG;fMRI and DTI;

Countries

China

Contacts

Public ContactLu Rongrong

Huashan Hospital, Fudan University

13764201659@163.com+86 21-52887820

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026