stroke
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Willing to sign informed consent; 2. Age between 20 to 75 years old, male or female; 3. Diagnosis in accordance with the key criteria point rasied in 1995 conference; 4. Confirmed by CT or MRI of the brain; 5. Paretic wrist motor impairment, no active wrist motion and strength between 0-1; 6. Disease duration above 6 months; 7. Vital signs stable.
Exclusion criteria
Exclusion criteria: 1. Cognitive impairment assessed by MMSE; 2. Auditory or vision impairment; 3. The questionnaire survey on motor and visual imagery shows that motor imagery cannot be performed; 4. Those with severe cardiopulmonary, liver, and kidney dysfunction who are not suitable for rehabilitation training (in the past 6 months, due to any cause of congestive heart failure (CHF) attack or worsening. Any need to change the dosing regimen, diet or hospitalization Heart failure is the onset of CHF; known valvular heart disease with CHF; thoracotomy cardiac surgery (eg, coronary artery bypass, valve replacement); acute myocardial infarction in the past 3 months; acute urgency on admission Signs or symptoms of infarction, including electrocardiographic findings; suspected aortic dissection on admission; acute arrhythmia with hemodynamic instability (including any tachycardia or bradycardia), etc.; liver dysfunction (Gu Bing, Asparagus is more than 1.2 times the normal range); blood creatinine and urea nitrogen are more than 1.2 times the normal range; existing acute or chronic lung disease); poor blood pressure and blood glucose control, blood pressure is detected as systolic blood pressure >= 140mmHg, diastolic blood pressure >= 90mmHg; 5. Patients with metal in the body (pacemaker, arterial stent, etc.), cannot complete MRI examination; 6. Pregnant or lactating women; 7. Poor compliance and unable to complete this training; 8. Those who participated in other clinical trials at the same time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| AROM of paretic wrist; | — |
Secondary
| Measure | Time frame |
|---|---|
| Brunnstrom (upper limb and hand);ARAT;Fugl Meyer for upper limb;Key muscle strength of upper limb;Key muscle tension of upper limb;ADL;EEG;fMRI and DTI; | — |
Countries
China
Contacts
Huashan Hospital, Fudan University