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The clinical efficacy of external application of mirabilite and rhubarb combined with intrathoracic chemotherapy in treating malignant pleural effusion: a prospective, randomized, controlled clinical trial

The clinical efficacy of external application of mirabilite and rhubarb combined with intrathoracic chemotherapy in treating malignant pleural effusion: a prospective, randomized, controlled clinical trial

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000034687
Enrollment
Unknown
Registered
2020-07-15
Start date
2020-07-01
Completion date
Unknown
Last updated
2020-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

malignant pleural effusion

Interventions

Sponsors

Longhua Hospital affiliated to Shanghai University of Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) At least 1 imaging examination (X-ray, B-ultrasound) showed moderate or above malignant pleural effusion, and the time between imaging examination and inclusion was = 60, ECOG PS score <= 2. (5) No serious heart, kidney, liver diseases or other therapeutic contraindications. (6) No chemotherapy or intrathoracic drug injection was performed within 1 month before the inclusion of treatment, except for diagnostic puncture. (7) Sign informed consent and receive medical treatment.

Exclusion criteria

Exclusion criteria: (1) End-stage patients with cachexia and severe hypoproteinemia, unable to complete one course of treatment. (2) Pregnant women, patients with mental disorders and those who do not cooperate with treatment.

Design outcomes

Primary

MeasureTime frame
QLQ C30 scale;

Secondary

MeasureTime frame
TCM syndrome score;Safety index;

Countries

China

Contacts

Public ContactZhen Lin

Longhua Hospital affiliated to Shanghai University of Chinese Medicine

2798968746@qq.com+86 13917359813

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026