Effects of dexmedetomidine combined with transversus abdominis plane block on postoperative gastrointestinal function in patients undergoing laparoscopic colorectal surgery

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000034681

Enrollment

Unknown

Registered

2020-07-14

Start date

2020-07-20

Completion date

Unknown

Last updated

2020-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Colorectal cancer

Interventions

Intervention group:Dexmedetomidine is pumped before the anesthesia induction and during the operation

Bilateral transversus abdominis plane block is performed before the anesthesia induction

Control group:The same dose of normal saline is pumped before the anesthesia induction and during the operation

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Ages 18 to 65 years; 2. ASA I~III; 3. Laparoscopic colorectal surgery is selected.

Exclusion criteria

Exclusion criteria: 1. Refusal to participate in this study; 2. Had colorectal surgery; 3. A definite contraindication to DEX; 4. Severe neurological,mental illness; 5. Serious cardiovascular and cerebrovascular diseases; 6. Severe respiratory disease; 7. The local infection of the TAPB puncture point; 8. Severe allergic reaction occurred during the operation.

Design outcomes

Primary

Measure	Time frame
Incidence of POGD;	—

Secondary

Measure	Time frame
Evaluation of postoperative nausea and vomiting;Opioid dosage;Pain assessment;Rehabilitation process;	—

Countries

China

Contacts

Public ContactChaolei Liu

Department of Anesthesiology, the Second Hospital of Hebei Medical University

verna521@163.com+86 15732028898

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026