Postoperative cognitive dysfunction
Conditions
Interventions
Group R:Group R was given remimazolam mesylate 6mg / kg / h for 5min before anesthesia induction.
Group M:Midazolam 0.04 mg / kg was given at the beginning of anesthesia induction
Sponsors
Department of Anesthesiology, Mianyang Central Hospital
Eligibility
Sex/Gender
All
Age
65 Years to No maximum
Inclusion criteria
Inclusion criteria: Methods: 120 elderly patients with liver cancer and hepatic hemangioma from July 2020 to March 2022 in Mianyang Central Hospital, Mianyang 404 hospital in Sichuan Province and Santai County Hospital in Mianyang City were selected. 120 elderly patients, aged >= 65 years, gender unlimited, ASA I - III, child Pugh grade A, were selected.
Exclusion criteria
Exclusion criteria: Patients with severe hypertension, neuropsychiatric diseases and heart, lung, liver and kidney function abnormalities; patients with severe sensory organ defects (such as vision and hearing impairment) or unable to communicate with the interviewers for other reasons to affect the test; taking sedatives, antidepressants, alcoholism; patients with known allergy to rimazolom toluenesulfonate and midazolam; preoperative MMSE score <= 17 and patients who do not agree to be selected or voluntarily withdraw their informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Operation time;Intraoperative blood loss;Infusion volume and Blood transfusion volume;Propofol dosage;Recovery time;Extubation time;heart rate(HR);Pulse Oxygen Saturation (SPO);mean arterial pressure (MAP);MMSE score;CAM score; | — |
Countries
China
Contacts
Public ContactJun Li
Department of Anesthesiology, Mianyang Central Hospital
Outcome results
None listed