Comparison of Dexmedetomidine and esketamine in preventing restlessness during awake period in children undergoing tonsillectomy

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000034676

Enrollment

Unknown

Registered

2020-07-14

Start date

2020-07-01

Completion date

Unknown

Last updated

2020-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Tonsillectomy

Interventions

Group A:10 mL1.0 g / kg dexmedetomidine was given intravenously 10 min before operation

Group B:10 mL 0.5mg / kg esketamine was given intravenously 10 min before operation

Group C:10 mL 0.9% sodium chloride injection was pumped intravenously 10 min before operation

Eligibility

Sex/Gender

All

Age

3 Years to 7 Years

Inclusion criteria

Inclusion criteria: 1. Aged 3-7 years; 2. ASA Grade I; 3. BMI18-30kg/m2.

Exclusion criteria

Exclusion criteria: 1. recent use of analgesics; 2. history of upper respiratory tract infection in the last 2 weeks; 3. cardiovascular disease; 4. History of Mental Retardation; 5. history of acid reflux disease; 6. other serious systemic disease.

Design outcomes

Primary

Measure	Time frame
HB;BP;SPO2;Epinephrine;noradrenaline;SAS;Pain Score;Sedation score;	—

Countries

China

Contacts

Public ContactShao Kun

Xinxiang Central Hospital of Henan Province

13781978391@126.com+86 13781978391

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026