Dry eye
Conditions
Interventions
Sponsors
Eye Hospital, China Academy of Chinese Medical Sciences
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. It fully meets the diagnostic criteria of western medicine for dry eyes and conforms to the syndrome differentiation of Traditional Chinese medicine for liver depression and Yin deficiency; 2. No serious cardiovascular and cerebrovascular diseases, mental diseases and other patients not suitable for clinical observation; 3. No other treatment received during the observation period; 4. Sign the informed consent form, voluntarily participate in and cooperate with the experimental subjects.
Exclusion criteria
Exclusion criteria: 1. Lactation or serious systemic chronic diseases; 2. Serious abnormal blood routine and liver and kidney function; 3. Congenital no tears, no tear ducts, neurological disorders, such as nerve is paralytic keratitis, lachrymal tube obstruction caused by large area of ocular surface damage, such as heat or chemical eye burn, eyelid defect and other active eye disease (including acute ocular surface inflammation), uncontrolled systemic disease, wearing contact lens, recently has a history of eye surgery or trauma, etc. 4. Use systemic antihistamines, anticholinergic drugs or other ophthalmic drugs that interfere with the efficacy; 5. If the subject considers it inappropriate to conduct a clinical trial; 6. Failure to adhere to treatment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Ocular Surface Disease Index; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tear Break-up Time;Schirmer I test;Fluorescent;OQAS Visual Quality Detector;Levels of Tear Inflammatory Factors;Protein Analysis of Tear Fluid;Quantitative Score Table of TCM Symptoms; | — |
Countries
China
Contacts
Public ContactLike Xie
Eye Hospital, China Academy of Chinese Medical Sciences
Outcome results
None listed