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Improvement effect of fucoidin intervention to pre-diabetes populations based on intestinal microecology

Effect and mechanism of fucoidin intervention on type 2 diabetes based on intestinal microecology

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000034668
Enrollment
Unknown
Registered
2020-07-14
Start date
2020-08-01
Completion date
Unknown
Last updated
2020-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pre-type 2 diabetes

Interventions

Intervention group:Intervention of fucoidin
Control group:Intervention of placebo

Sponsors

Zhengzhou University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. IFG: 5.6mmol/l = FPG < 7.0mmol/l and 2h-ogtt < 11.1mmol/l; IGT: FPG < 7.0mmol/l and 7.8mmol/l = 2h-ogtt < 11.1mmol/l; meeting any of the above criteria can be included; 2. Patients aged between 18 and 70 years old; 3. Patients with informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with new or current diabetes mellitus (FPG = 7.0 mmol / L or 2hPG = 11.1 mmol / L) or under hypoglycemic therapy; 2. Patients with gastrointestinal diseases, such as gastritis, enteritis, ulcers, etc; 3. Patients who are taking other antibiotics or microbial preparations that may affect the results, such as penicillin or Lactobacillin tablets; 4. Pregnant women or lactation; 5. Patients with serious health problems who are not suitable to participate in the study (such as cancer, surgery in the past six months or major surgery in the near future, etc.); 6. Patients with mental incapacity, unwillingness to participate or language disorders that hinder full understanding or cooperation.

Design outcomes

Primary

MeasureTime frame
FBG;Fins;

Secondary

MeasureTime frame
HbA1c;TG;TC;LDL;HDL;TNF-a;IL-1ß;IL-6;

Countries

China

Contacts

Public ContactLiu Yaping

Zhengzhou University

liuyaping_tang@163.com+86 15639082849

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026