FindTrial
Sign In

Efficacy of an Intraoperative Intravenous Bolus Dose Dexmedetomidine for the Prevention of Postoperative Catheter-Related Bladder Discomfort in Male Patients Undergoing Transurethral Resection of Bladder Tumors: a Double-Blinded, Randomized Clinical Trial.

Efficacy of an Intraoperative Intravenous Bolus Dose Dexmedetomidine for the Prevention of Postoperative Catheter-Related Bladder Discomfort in Male Patients Undergoing Transurethral Resection of Bladder Tumors: a Double-Blinded, Randomized Clinical Trial.

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000034657
Enrollment
Unknown
Registered
2020-07-13
Start date
2020-07-14
Completion date
Unknown
Last updated
2020-07-20

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Catheter-Related Bladder Discomfort

Interventions

Group A:intravenous infusion of 0.9% saline 1ml/kg 15 minutes before the end of surgery
Group B:intravenous infusion of dexmedetomidine 0.2ug/kg 15 minutes before the end of surgery
Group C:intravenous infusion of dexmedetomidine 0.5ug/kg 15 minutes before the end of surgery
Group D:intravenous infusion of dexmedetomidine 1ug/kg 15 minutes before the end of surgery

Sponsors

Sun Yat-Sen University Cancer Center
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
20 Years to 79 Years

Inclusion criteria

Inclusion criteria: Male; American Society of Anesthesiologists (ASA) physical status I and II; aged 20 to 79 year; scheduled transurethral resection of bladder tumor.

Exclusion criteria

Exclusion criteria: Bladder outflow obstruction; Overactive bladder;Neurogenic bladder; Mental or neurological diseases; Liver or renal function disfunction; BMI > 30 kg/m2; Acute or chronic pain and/or use of analgesic medication; Cardiovascular disease (CVD); Arrhythmology.

Design outcomes

Secondary

MeasureTime frame
The incidences of catheter-related bladder discomfort levels above a moderate grade at 1, 6,24,48h postoperatively;The severity of catheter-related bladder discomfort at 0, 1, 6, 24 and 48 h postoperatively;The postoperative pain score NRS;The rescue medications (tramadol and tolterodine);Hospitalization duration;Time to extubation;Patient satisfaction;—

Primary

MeasureTime frame
The incidence of catheter-related bladder discomfort above a moderate grade at 0h postoperatively;—

Countries

China

Contacts

Public ContactCao Longhui

Sun Yat-Sen University Cancer Center

caolh@sysucc.org.cn+86 13826092036

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026