Cardiovascular disease
Conditions
Interventions
Placebo group:placebo 150 mg/day
Fruitflow group:Fruitflow 150 mg/day
Aspirin group:Aspirin 100 mg/day
Fruitflow+Aspirin group:Fruitflow 150 mg/day+Aspirin 100 mg/day
Sponsors
Beijing Hospital
Eligibility
Sex/Gender
All
Age
50 Years to 80 Years
Inclusion criteria
Inclusion criteria: The inclusion criteria adhered to the Chinese expert consensus on aspirin application guidelines. The subject has hypertension but his blood pressure is well controlled (<150/90 mmHg), or the subject has diabetes but his blood glucose is well controlled. The platelet aggregation rate of these subjects reached more than 50% in ADP- and collagen-activated platelets.
Exclusion criteria
Exclusion criteria: The exclusion criteria were blood pressure >=160/100 mmHg, platelet count < 100x10^9/L, prothrombin time outside the normal reference range, the chronic use of medications and nutritional supplements, allergy to tomatoes or their ingredients, intolerance or allergy to ASA, contraindications for ASA, and fecal occult blood positive test. Moreover, according to the researchers judgment, individuals with serious hematological diseases, digestive diseases, organic diseases of the heart, liver, or kidneys, severe liver or kidney dysfunction, or metabolic, endocrine, or nervous system diseases were also excluded
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| aggregation rate of platelet;Clotting function test;blood routine examination;biochemical test;blood pressure;Fecal occult blood test; | — |
Secondary
| Measure | Time frame |
|---|---|
| Height;Weight; | — |
Countries
China
Contacts
Public ContactRuomei Qi
Beijing Hospital
Outcome results
None listed