The median effective dose of peak airway pressure in left paratracheal esophagus insufflation of air induction of anesthesia with Dixon’s Up-and-Down method:A Prospective, Randomized, single-Blind Study

A sequential method was used to determine half of the effective peak airway pressure of mask ventilation esophageal intake during the induction period of general anesthesia

Status

Recruiting

Phases

Early Phase 1

Study type

Observational

Source

ChiCTR

Registry ID

ChiCTR2000034633

Enrollment

Unknown

Registered

2020-07-12

Start date

2020-07-12

Completion date

Unknown

Last updated

2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Esophagus intake during induction of general anesthesia

Interventions

Case series:Lower or increase airway pressure

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: Select 2020 March in line, the first hospital of jiaxing city 40 cases of patients with general anesthesia, ASA class I - II, aged 18 to 80 years old, body mass index (BMI) ? 26 kg/m2.

Exclusion criteria

Exclusion criteria: Patients with indwared gastric tube, patients with definite risk of aspiration, oropharyngeal and facial diseases, and patients with nasal polyps.

Design outcomes

Primary

Measure	Time frame
Peak airway pressure at the end of ventilation;Exhaled tidal volume;Pco2 at end of breath;Antrum cross-sectional area before and after ventilation;	—

Secondary

Measure	Time frame
Oxygen concentration at the end of breath;	—

Countries

China

Contacts

Public ContactWei Deng

Jiaxing First Hospital

dengwei1992868@163.com+86 19884340796

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026