inherited retinal dystrophy
Conditions
Interventions
Case series:Nil
Sponsors
Shanghai Childrens Hospital
Eligibility
Sex/Gender
All
Age
4 Years to 18 Years
Inclusion criteria
Inclusion criteria: 1. IRDS patients with confirmed gene mutation / translocation / deletion; 2. Aged 4-18years; 3. Sign informed consent; 4. Complete 4 basic eye examinations: corrected visual acuity; fundus photography; Oct; ERG
Exclusion criteria
Exclusion criteria: 1. Failure to follow study or follow-up procedures; 2. It has participated in other intervention treatment studies, such as new drugs, stem cell therapy and transgenic treatment; 3. Patients with severe systemic diseases, mental retardation, mental illness, etc., who can not accept eye examination; 4. There are traumatic retinopathy, retinal inflammatory disease, paraneoplastic retinopathy, drug toxicity and rare diseases, such as diffuse unilateral subacute optic nerve retinitis; 5. At the first visit, both eyes showed no light perception; 6. Both eyes have a history of intraocular surgery; 7. The researchers believe that they need to be excluded.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proportion of deterioration in natural course of follow-up in patients with IRDS; | — |
Countries
China
Contacts
Public ContactTong Qiao
Department of Ophthalmology, Shanghai Children‘s Hospital
Outcome results
None listed