cerebral infarction
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. The diagnosis of cerebral infarction conforms to the diagnostic criteria of Chinese Guidelines for diagnosis and Treatment of Acute Ischemic Stroke 2018. 2. Symptom onset = 18 years old; 4. Symptoms of neurological deficits, NIHSS score >= 1, thrombolytic indications, and RT-PA intravenous thrombolytic therapy. 5. Prior to thrombolysis, the informed consent was signed by the patient or family members.
Exclusion criteria
Exclusion criteria: 1. Patients with contraindications to venous thrombolysis; 2. Failure to complete intravenous thrombolysis due to various reasons; 3. Patients with data deficiency; 4. Patients with final diagnosis of apoplexy; 5. Patients with disturbance of consciousness, language communication or understanding; 6. Patients who cannot cooperate with the examination; 7. Patients undergoing endovascular treatment such as bridging arterial thrombolysis and mechanical thrombectomy; 8. Patients who are participating in other clinical studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| NIHSS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| gander;age;Previous medical history;taken any antiplatelet drugs or anticoagulants before illness;state of consciousness;Time to start treatment after onset;DNT time;blood pressure;RTPA actual dose;fasting blood-glucose;blood routine examination;D - dimer;blood lipid;Four coagulation;liver function;renal function;Glycosylated hemoglobin;TOAST subtypes;Location and nature of cerebral infarction;mRS score;Hypersensitive C-reactive protein;Dry electrode quantitative electroencephalogram;Hamilton Anxiety/Depression Scale score;MMSE score;MoCA score;Pittsburgh sleep quality Index;adverse reaction;Neuro11 score; | — |
Countries
China
Contacts
Department of Neurology, Shenzhen People's Hospital