Cervical cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy people without HPV infection and cervical lesions; 2. Patients with low-grade squamous intraepithelial lesions and high-grade squamous intraepithelial lesions; 3. Patients with cervical cancer.
Exclusion criteria
Exclusion criteria: 1. Any skin condition identified by the physician that may affect the conduct of the study or increase the risk of the test subjects, including any open or healed cuts / cuts, abrasions or skin breaks in the test area as determined by the gynecologist; 2. Menstruation at the time of treatment; 3. Patients who have used antibiotics, antifungal drugs, topical steroids or antiviral drugs (oral or local use in the test area) within 7 days before using or visiting the hospital; 4. Patients who have or had genital herpes; 5. Patients with vaginal infection (including Candida infection or bacterial vaginosis), vulvar infection, urinary tract infection, sexually transmitted infection (chlamydia, gonorrhea, trichomoniasis, genital herpes); 6. 48 hours before the visit, use emulsion, talcum powder, ointment, cream, perfume or oil in the test area. 7. the use of flushing material, vaginal drug, vaginal suppository, female deodorant spray, wet towel or lubricant to the genital area within 48 hours before treatment; 8. Those who had sex within 48 hours before the visit; 9. Patients receiving treatment for skin problems in the test area; 10. The object who has bathed or swam within 4 hours before seeing the doctor; 11. Objects that have been shaved, waxed or depilated in the test area 48 hours before the visit; 12. Patients with type I or II diabetes mellitus; 13. Hepatitis or HIV positive patients; 14. Patients with other diseases not suitable for the experiment, such as immunosuppression.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| low molecular weight compound;flora; | — |
Secondary
| Measure | Time frame |
|---|---|
| bifunctional enzyme;general condition;HPV;cytology;pathology report; | — |
Countries
China
Contacts
The Affiliated Wuxi Maternity and Child Health Care Hospital of Nanjing Medical University