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Development of early warning index for cervical cancer based on vaginal microecological

Popularization and demonstration of vaginal microecology standardized diagnosis and treatment for early warning and intervention of cervical cancer

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000034596
Enrollment
Unknown
Registered
2020-07-11
Start date
2020-07-15
Completion date
Unknown
Last updated
2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical cancer

Interventions

null:no intervention

Sponsors

The Affiliated Wuxi Maternity and Child Health Care Hospital of Nanjing Medical University
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: 1. Healthy people without HPV infection and cervical lesions; 2. Patients with low-grade squamous intraepithelial lesions and high-grade squamous intraepithelial lesions; 3. Patients with cervical cancer.

Exclusion criteria

Exclusion criteria: 1. Any skin condition identified by the physician that may affect the conduct of the study or increase the risk of the test subjects, including any open or healed cuts / cuts, abrasions or skin breaks in the test area as determined by the gynecologist; 2. Menstruation at the time of treatment; 3. Patients who have used antibiotics, antifungal drugs, topical steroids or antiviral drugs (oral or local use in the test area) within 7 days before using or visiting the hospital; 4. Patients who have or had genital herpes; 5. Patients with vaginal infection (including Candida infection or bacterial vaginosis), vulvar infection, urinary tract infection, sexually transmitted infection (chlamydia, gonorrhea, trichomoniasis, genital herpes); 6. 48 hours before the visit, use emulsion, talcum powder, ointment, cream, perfume or oil in the test area. 7. the use of flushing material, vaginal drug, vaginal suppository, female deodorant spray, wet towel or lubricant to the genital area within 48 hours before treatment; 8. Those who had sex within 48 hours before the visit; 9. Patients receiving treatment for skin problems in the test area; 10. The object who has bathed or swam within 4 hours before seeing the doctor; 11. Objects that have been shaved, waxed or depilated in the test area 48 hours before the visit; 12. Patients with type I or II diabetes mellitus; 13. Hepatitis or HIV positive patients; 14. Patients with other diseases not suitable for the experiment, such as immunosuppression.

Design outcomes

Primary

MeasureTime frame
low molecular weight compound;flora;

Secondary

MeasureTime frame
bifunctional enzyme;general condition;HPV;cytology;pathology report;

Countries

China

Contacts

Public ContactChen Daozhen

The Affiliated Wuxi Maternity and Child Health Care Hospital of Nanjing Medical University

chendaozhen@163.com+86 510-82725161

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026