Gastric cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. 35 to 65 years old; 2. ASA grade I to II; 3. with correct surgical indications; 4. patients knew about the study and signed informed consent.
Exclusion criteria
Exclusion criteria: 1. cognitive dysfunction before surgery; 2. history of severe hypertension or heart disease; 3. severe liver and kidney dysfunction; 4. hematological diseases and coagulation abnormalities; 5. BMI > 30kg/m2; 6. distant organ metastasis; 7. recent take of antidepressant drugs, sedatives, or analgesics; 8. allergic to research drug; 9. past history of abdominal surgery; 10. recent history of radiotherapy or chemotherapy; 11. laparoscopic radical gastrectomy changed to open surgery; 12. perioperative blood transfusion; 13. contraindications to regional block; 14. regional block complications such as puncture injury at puncture site, infection bleeding, and local anesthetic poisoning; 15. failure to complete intraoperative data collection and postoperative follow-up.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain Visual Analogue Scale;CD3+;CD4+;CD4+/CD8+;Natural killer cell; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sufentanil dosage; | — |
Countries
China
Contacts
Department of Anesthesiology, The Second Hospital of Shandong University