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Effect of ultrasound-guided quadratus lumborum block on postoperative analgesia and immune function in patients undergoing laparoscopic radical gastrectomy

Effect of ultrasound-guided quadratus lumborum block on postoperative analgesia and immune function in patients undergoing laparoscopic radical gastrectomy

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000034592
Enrollment
Unknown
Registered
2020-07-11
Start date
2020-07-16
Completion date
Unknown
Last updated
2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric cancer

Interventions

Experimental group:quadratus lumborum block and patient control intravenous analgesia

Sponsors

The Second Hospital of Shandong University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
35 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. 35 to 65 years old; 2. ASA grade I to II; 3. with correct surgical indications; 4. patients knew about the study and signed informed consent.

Exclusion criteria

Exclusion criteria: 1. cognitive dysfunction before surgery; 2. history of severe hypertension or heart disease; 3. severe liver and kidney dysfunction; 4. hematological diseases and coagulation abnormalities; 5. BMI > 30kg/m2; 6. distant organ metastasis; 7. recent take of antidepressant drugs, sedatives, or analgesics; 8. allergic to research drug; 9. past history of abdominal surgery; 10. recent history of radiotherapy or chemotherapy; 11. laparoscopic radical gastrectomy changed to open surgery; 12. perioperative blood transfusion; 13. contraindications to regional block; 14. regional block complications such as puncture injury at puncture site, infection bleeding, and local anesthetic poisoning; 15. failure to complete intraoperative data collection and postoperative follow-up.

Design outcomes

Primary

MeasureTime frame
Pain Visual Analogue Scale;CD3+;CD4+;CD4+/CD8+;Natural killer cell;

Secondary

MeasureTime frame
Sufentanil dosage;

Countries

China

Contacts

Public ContactChang Feng

Department of Anesthesiology, The Second Hospital of Shandong University

fengchang180@163.com+86 17660085521

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 5, 2026