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The effect of plasma concentration decline induced by the co-administration of meropenem on the anti-epileptic efficacy of valproic acid

The effect of meropenem on the antiepileptic effect of valproic acid

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000034567
Enrollment
Unknown
Registered
2020-07-10
Start date
2010-01-01
Completion date
Unknown
Last updated
2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

epilepsy and infection

Interventions

Case series:None

Sponsors

Neurology Department, Nanfang Hospital, Southern Medical University
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. aged>=14 years old; 2. diagnosed as epilepsy or status epilepticus (SE).

Exclusion criteria

Exclusion criteria: 1. VPA not used concomitantly with MEPM or co-administration for<24h; 2. VPA used for seizure prophylaxis3) data missing (including the record of seizure attacks and/or the assessment of infection).

Design outcomes

Secondary

MeasureTime frame
seizure duration;concomitant AEDs;—

Primary

MeasureTime frame
seizure frequency;—

Countries

China

Contacts

Public ContactShengnan Wang

Nanfang Hospital, Southern Medical University

wsnpumc@smu.edu.cn+86 13427564191

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 6, 2026