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Minimally invasive microwave ablation combined with bone cement for pain relief in patients with spinal metastases from lung cancer

Minimally invasive microwave ablation combined with bone cement for pain relief in patients with spinal metastases from lung cancer

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000034543
Enrollment
Unknown
Registered
2020-07-09
Start date
2020-07-09
Completion date
Unknown
Last updated
2021-08-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Spinal metastasis of lung cancer

Interventions

Microwave:Microwave and bone cement
Bone cement:bone cement

Sponsors

Guangdong Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-80 years; 2. At least one osteolystic spinal metastasis of lung cancer confirmed by preoperative imaging and intraoperative frozen pathology; 3. Preoperative VAS score of the affected vertebra >= 4.

Exclusion criteria

Exclusion criteria: 1. Skin disease or skin infection around, local puncture treatment contraindications; 2. Patients who had received local radiotherapy before admission; 3. The patients with comminuted fracture of vertebrae, or the fracture block protruding into the spinal canal, or with symptoms of nerve compression, or the tumor widely invading the surrounding soft tissue (such as nerve root and spinal cord), can not be treated with bone cement plastic surgery and need open surgery; 4. Unclear mind or low education, unable to correctly evaluate clinical performance; 5. Severe heart disease, renal failure, liver failure, coagulation disorder and other serious systemic diseases, unable to tolerate surgery; 6. Hypersensitive reaction history to bone cemen.

Design outcomes

Primary

MeasureTime frame
VAS;Local recurrence rate;Incidence of vertebral fracture;Quality of life score EQ-5D;ODI score;morphine equivalent daily dose;

Countries

China

Contacts

Public ContactYu Zhang

Guangdong Provincial People's Hospital

luck_2001@126.com+86 13602744495

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026