Painless colonoscopy
Conditions
Interventions
experimental group:Induction and maintenance of anesthesia with remazolam tosylate
control group:Propofol for induction and maintenance anesthesia
Sponsors
Affiliated Hospital of Southwest Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 60 Years
Inclusion criteria
Inclusion criteria: 1) Aged 18- 60 years, gender is not limited; 2) General anesthesia patients receiving routine colonoscopy diagnosis and treatment; 3) ASA score is grade I or II; 4) 18kg/m2 < BMI < 30kg/m2.
Exclusion criteria
Exclusion criteria: 1) Patients to be intubated; 2) Patients with difficult airway; 3) Anemia or thrombocytopenia, HB = 2.5 * ULN, TBIL >= 1.5 * ULN; 5) Renal function is abnormal, and serum creatinine is greater than the normal upper limit; 6) Hypertensive patients whose blood pressure is not satisfactorily controlled by antihypertensive drugs (systolic pressure >= 160mmHg and/or diastolic pressure >= 100 mmHg); 7) Systolic blood pressure <= 90 mmHg; 8) Pregnant or breast-conserving women; 9) Patients allergic to benzodiazepines and opioids; 10) Attended clinical trials of other drugs as subjects in the past 3 months; 11) The researcher thinks that it is inappropriate for patients to participate in this test or the patients themselves refuse to do so.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Number of airway interventions;Indicators of ventilation and oxygenation;Hemodynamic index;Efficacy index;Calm Allen Su Time;Incidence of adverse reactions; | — |
Primary
| Measure | Time frame |
|---|---|
| Time from completion of anesthesia induction administration to first airway intervention; | — |
Countries
China
Contacts
Public ContactBai YiPing
Affiliated Hospital of Southwest Medical University
Outcome results
None listed