Obstructive sleep apnea-hypopnea syndrome
Conditions
Interventions
experimental group:Dexmedetomidine and propofol
control group:Dexmedetomidine only
Sponsors
Shenzhen Second People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients who voluntarily participate in the study and sign the informed consent form voluntarily; 2. Patients aged 18-65 years; 3. Patients with snoring were diagnosed with BMI of 24-31 kg / m2 and SpO2 > 95% when awake; 4. Patients who have completed sleep polysomnography monitoring and other examinations before operation and have received CPAP treatment for more than one week.
Exclusion criteria
Exclusion criteria: 1. Patients who refused to participate in the trial; 2. Patients with poor control of pregnancy, hypertension, coronary heart disease, cerebrovascular disease and COPD history; 3. Patients with sinus bradycardia or II degree - III degree atrioventricular block indicated by ECG; The patient had been operated on for 3 months; 5. Patients with severe deformity of mandible or maxilla; 6. Patients allergic to dexmedetomidine or propofol.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Completion rate; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time to fall asleep;Endoscopy time;Time to wakeup;Haemodynamic and respiratory data;Bispectral index score;Adverse event rate;Satisfaction of patients and endoscopic performer; | — |
Countries
China
Contacts
Public ContactXinping Yang
Shenzhen Second People's Hospital
Outcome results
None listed