Prophylactic intra-arterial injection of lidocaine prevents trigeminocardiac reflex during endovascular embolization: a randomized double-blind controlled trial

The preventive effect of intra-arterial injection of lidocaine on trigeminocardiac reflex during endovascular embolization

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000034503

Enrollment

Unknown

Registered

2020-07-07

Start date

2020-07-02

Completion date

Unknown

Last updated

2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

cerebrovascular malformations

Interventions

control group:normal saline

experimental group:Local intravascular injection of lidocaine

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: The patients who underwent Onyx embolization due to cerebrovascular malformations in our center from December 2019 to December 2020 were selected successively.

Exclusion criteria

Exclusion criteria: (1) Those who could not provide informed consent and communication difficulties before surgery; (2) Patients with serious cardiovascular diseases; (3) Allergic to any anesthetic drug to be studied; (4) Patients with unclear consciousness before operation or severe complications during operation, resulting in postoperative consciousness disorder; (5) Long-term use of psychiatric drugs; (6) Refuse to enroll patients.

Design outcomes

Primary

Measure	Time frame
Heart Rate;ABP;Incidence of TCR;	—

Countries

China

Contacts

Public ContactYouli Hu

The First Affiliated Hospital of Nanjing Medical University / Jiangsu Province Hospital

huyouli@hotmail.com+86 13951996560

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026