Ischemic stroke
Conditions
Interventions
experimental group:use of butylphthalide and routine secondary prophylaxis
control group: routine secondary prophylaxis
Sponsors
Northwest University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. The patient's age > 18 years; 2. Hospitalized patients with ischemic stroke diagnosed by clinical symptoms or signs. The clinical manifestations are the symptoms and characteristics of sudden onset, rapid occurrence of localized or diffuse brain damage, and the defect of neurological function is consistent with the distribution of blood vessels. 3. 24 hours after admission, there were neurological examination results and imaging (CT/CTA, MRI/MRA) changes. 4. Voluntarily participate and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients who were discharged from hospital, transferred to other departments and died within 24 hours. 2. Patients with severe heart, liver, kidney and other organ dysfunction or severe systemic diseases are expected to survive for less than one year. 3. Patients cannot be followed up continuously. 4. Hepatic and renal dysfunction. 5. Allergic to butylphthalide. 6. Patients during pregnancy, lactation and planned pregnancy. 7. Patients with severe mental disorders and dementia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Recurrence rate of stroke; | — |
Secondary
| Measure | Time frame |
|---|---|
| NIHSS;mRS;clinical cardiovascular events;Adverse reaction; | — |
Countries
China
Contacts
Public ContactZhao Gang
Air Force Military Medical University
Outcome results
None listed