migraine without aura
Conditions
Sponsors
Chengdu University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 55 Years
Inclusion criteria
Inclusion criteria: (1) men or women aged 18–55 years; (2) right handed, length of education >=6 years; (3) a history of migraine of at least 1 year with the first onset before the age of 50 years; (4) migraine attacks >=2 times and number of migraine days <15 days per month during the past 3 months and baseline observation; (5) completion of the baseline headache diary; (6) provision of written informed consent.
Exclusion criteria
Exclusion criteria: (1) any combination of head trauma history, secondary headache, tension-type headache, intermittent-type headache, cluster-type headache, or cardiovascular and digestive diseases; (2) a history of major intestinal resection or gastrointestinal surgery; (3) presence of psychiatric disease, infection, bleeding disorders, or allergic constitution; (4) pregnancy, lactation, or plans to become pregnant within 6 months; (5) inability to understand or fill in a headache diary; (6) nuclear magnetic contraindications, such as claustrophobia; (7) a history of taking antibiotics or receiving acupuncture therapy for 3 days or more in the past 3 months; (8) long-term use of analgesic drugs and medications to prevent migraine attacks; (9) participation in a similar study in the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Frequency of migraine attacks ;Intensity of migraine ;fMRI;Gut microbiota; | — |
Secondary
| Measure | Time frame |
|---|---|
| Days of migraine attacks;MSQ;GSRS;BAI;BDI; | — |
Countries
China
Contacts
Public ContactLing Zhao
Chengdu University of Traditional Chinese Medicine
Outcome results
None listed