Osteoarthritis
Conditions
Interventions
OA Group:Nil
OA-DM Group:Nil
Non-OA group:Nil
Sponsors
Zhongshan Chinese Medicine Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: (1) The diagnosis of unilateral osteoarthritis of the knee is clear, and it is classified into three or four grades. The non-operative treatment is ineffective. (2) The patients and their families have consented, the compliance is high, and the patients have accepted all kinds of tests before and after operation. (3) The patient underwent unilateral total knee arthroplasty for the first time. (4) There were no abnormal platelet and coagulation before operation.
Exclusion criteria
Exclusion criteria: (1) Complicated with severe liver and renal dysfunction; (2) Patients with high risk factors for thrombosis, such as heart failure, Acute respiratory distress syndrome, etc. (3) Inability to cooperate with treatment for mental illness; (4) Patients with a history of malignant tumor; (5) A history of thrombosis and pulmonary embolism (including intramuscular vein thrombosis) , cerebral embolism and cerebral infarction; (6) Patients with Hemoglobin < 100g / L.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| N-GLYCOSYLATION proteomics in healthy volunteers;N-glycosylated proteomics of cartilage in patients with Oa;N-glycosylated proteomics of cartilage in patients with type 2 diabetes Mellitus and OA; | — |
Countries
China
Contacts
Public ContactTang Jianbang
Zhongshan Chinese Medicine Hospital
Outcome results
None listed