Facial paralysis
Conditions
Interventions
Intervention group:Combination of both hypoglossal-facial nerve anastomosis and ansa cervicalis-hypoglossal nerve anastomosis
control group:Hypoglossal - facial nerve anastomosis
Sponsors
Xinhua Hospital Affiliated to Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: (1) Aged between 18-70 years, regardless of gender; (2) Meets the diagnostic criteria of "Peripheral Facial Paralysis" and the HB grade of facial paralysis is over Grade V; (3) If the anatomy continuity of patients' facial nerve is not interrupted, patients need underwent standardized conservative treatment for more than 6 months; (4) Before the operation, the amplitude of the electromyography on the affected side decreases by more than 70% compared with the healthy side; (5) The hypoglossal nerve function is normal; (6) Agree to participate in this topic and sign an informed letter.
Exclusion criteria
Exclusion criteria: (1) EMG indicates that the fibrillation potential disappears at rest, or the multiphase reaction potential cannot be induced during active exercise; (2) Patients with bilateral peripheral facial paralysis; (3) Patients with neurofibromatosis; (4) Patients with paralysis after poisoning and radiotherapy; (5) Severe systemic diseases such as circulation, breathing, blood, etc. are not suitable for general anesthesia; (6) Patients with mental illness; (7) Those who participated in other clinical trials within 3 months before the start of this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| lingual atrophy grade ; | — |
Secondary
| Measure | Time frame |
|---|---|
| Tongue motor function score scale (ROM);Tongue disability index;Sunnybrook Score;Facial nerve evaluation system 2.0 (FNGS 2.0);17/5000 Nottingham facial nerve grading scale;FaCE scale;Neuroelectrophysiology; | — |
Countries
China
Contacts
Public ContactShiting Li
Xinhua Hospital Affilated to Shanghai Jiaotong University School of Medicine
Outcome results
None listed