gallstone disease
Conditions
Interventions
Sponsors
Chengdu University of Traditional Chinese Medicine
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Meet the diagnostic criteria for gallstone disease set by the EASL in 2016; 2. Aged between 18 and 60 years and right-handed; 3. have not taken any cholagogic drugs within 1 month; 4. not participating in any other clinical trials in the past three months; 5. having signed informed consent.
Exclusion criteria
Exclusion criteria: 1. calculus in bile duct; 2. acute cholecystitis, acute suppurative, gangrenous, incarcerated cholecystitis and perforation of gallbladder with diffuse peritonitis, etc.; 3. with serious complications or primary diseases such as cardiovascular, liver, kidney, endocrine and hematopoietic system; 4. with severe digestive system diseases, such as peptic ulcer, upper gastrointestinal hemorrhage, gastric tumor, Crohn's disease, irritable bowel syndrome, etc; 5. WBC > 12*10^9/L with systemic inflammatory response; 6. having a history of corticosteroid treatment in the past month; 7. having a history of anti-infective drug therapy (excluding cephalosporins) in the past month; 8. with high anxiety and depression (SAS >= 70 or SDS >= 72) and those with mental illness; 9. with obvious headache, migraine, head injury history and obvious pain in other parts; 10. women being in pregnancy or lactation; or 11. having contraindications of MRI scans such as claustrophobia or implanted ferromagnetic metal; 12. with head space occupying disease.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| task fMRI data; | — |
Secondary
| Measure | Time frame |
|---|---|
| appetite test;Numeric Rating Scale; | — |
Countries
China
Contacts
Public ContactSun Ruirui
Outcome results
None listed