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Study for a community advantage plan and its mechanism of ''Shan-Cai Yi-Zhi moxibustion'' combined with multiple tasks intervention MCI for preventing the senile dementia based on a digital platform

Study for a community advantage plan and its mechanism of ''Shan-Cai Yi-Zhi moxibustion'' combined with multiple tasks intervention MCI for preventing the senile dementia based on a digital platform

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000034365
Enrollment
Unknown
Registered
2020-07-03
Start date
2018-01-01
Completion date
Unknown
Last updated
2020-07-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mild Cognitive Impairment, MCI

Interventions

Group 1:''San-Cai Yi-Zhi'' moxibustion
Group 2:Multisensory stimulation + Simultaneous multi-tasking
Group 3:''San-Cai Yi-Zhi'' moxibustion + multi-sensory stimulation + body movement
Group 4:Oral donepezil hydrochloride

Sponsors

Chengdu University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) It meets the diagnostic criteria of Western medicine for MCI; (2) A history of memory impairment of at least 3 months with the first onset; (3) Aged Between 50 and 85 years old; (4) Without heart diseases, cerebrovascular diseases, liver and kidney dysfunction and other serious diseases of important organ function; (5) No history of neurological or mental illness; (6) Impairment of cognitive function caused by non-vascular factors and depression; (7) Accumulated education time is at least 1 year; (8) Voluntary participation and signed informed consent.

Exclusion criteria

Exclusion criteria: (1) Combined with aphasia or severe visual or hearing impairment; (2) In the past month, I have used Traditional Chinese medicine, Western medicine or acupuncture to treat cognitive function; (3) Identify brain structural abnormalities that lead to cognitive impairment, such as brain trauma, intracranial space-occupying lesions, or congenital mental retardation; (4) Alcohol or drug dependence in the last 6 months prior to study inclusion or at present, according to DSM-II-R; (5) Participating in other clinical trials.

Design outcomes

Primary

MeasureTime frame
Event-related potential P300;Brain MRI;Serum Tau;Serum Phosphorylated tau;Serum A beta1-42;

Countries

China

Contacts

Public ContactZhang Hong

Chengdu University of Traditional Chinese Medicine

104995985@qq.com+86 13308199375

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026