Mild Cognitive Impairment (MCI)
Conditions
Interventions
Case series:no intervention
Sponsors
School of Public Health, Tianjin Medical University
Eligibility
Sex/Gender
All
Age
60 Years to No maximum
Inclusion criteria
Inclusion criteria: Community-based stable natural population aged 60 or older
Exclusion criteria
Exclusion criteria: 1. Neurological examination found the sign of local central nerve obstruction such as obvious paralysisunilateral sensory disturbance and aphasia etc, history of cerebrovascular diseases (hemorrhagic and ischemic stroke), brain injury or bone fracture; 2. Medical diseases such as asthmatic bronchitis, severe hypertension, angina pectoris and severe infection; 3. Psychotic patients with evident anxiety and depressed emotion and subjects with endocrine system history of disease(hyperthyroidism, thyroid hypofunction, systemic lupus eythematosus, rheumatoid arthritis); 4. Newly discovered or advanced tumor; 5. Visual perception,auditory perceptual disorders or languages communication difficulties, all of which may influence measurement of cognitive function; 6. Alcohol dependence and other psychoactive substance abuse such as antipsychotic drug,benzodiazepines or taking medicine influencing cognitive function.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive function (MMSE score);Folate and methionine circulating metabolites;Luckocyte telomere length and damage;Peripheral blood inflammatory cytokines;Related gene expression; | — |
Countries
China
Contacts
Public ContactGuowei Huang
School of Public Health, Tianjin Medical University
Outcome results
None listed