gastric cancer
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. both gender; 2. Aged >= 18 years; 3. Received 2-4 cycles of neoadjuvant chemotherapy with 5-fluorouracil 3 weeks before operation; 4. Schedule to undergo laparoscopic or robot-assisted gastrectomy and digestive tract reconstruction; 5. Diagnosed as gastric adenocarcinoma by histopathological examination; 6. Surgical treatment can be performed according to the evaluation of MDT before operation.
Exclusion criteria
Exclusion criteria: 1. Refuse to participate in the experiment. 2. Emergency surgery is required. 3. Receive antibiotics and / or glucocorticoids within 10 days before operation. 4. Autoimmune diseases. 5. ASA grade IV or V. 6. Existing bacterial infection. 7. Intolerance or allergic to probiotics.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| postoperative complications;postoperative first bowel movement;postoperative first flatus; | — |
Secondary
| Measure | Time frame |
|---|---|
| WBC count;NEUT;NEUT%;CRP;????;albumin;body temperature;postoperative hospital stay;postoperative hospitalized cost;30 days readmission rate;30 days motality;duration of antibiotics treatment; | — |
Countries
China
Contacts
Affiliated Hospital of Qingdao University