A randomized controlled clinical study for the rhBMP-2 and allogeneic bone mixture transplant combined with external counterpulsation in treating femoral neck fracture.

Clinical study of the rhBMP-2 and allogeneic bone mixture transplant combined with external counterpulsation in treating femoral neck fracture.

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2000034312

Enrollment

Unknown

Registered

2020-07-01

Start date

2020-07-01

Completion date

Unknown

Last updated

2020-07-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Femoral neck fracture.

Interventions

Control group:Closed reduction and screw fixation

experimental group:rhBMP-2 and allogeneic bone mixture transplant combined with external counterpulsation

Eligibility

Sex/Gender

All

Age

18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Simple femur neck fracture; 2. Aged 18-80 years; 3. Fresh fracture, not yet treated accordingly; 4. Approved by the hospital ethics committee; 5. Patients and family members have informed consent.

Exclusion criteria

Exclusion criteria: 1. Pathological fractures; 2. The hemiplegia of the limb is present before fracture, and the ability to walk independently is lost; 3. Important organs are accompanied by severe insufficiency or other serious diseases; 4. Lower limb venous thrombosis.

Design outcomes

Primary

Measure	Time frame
facture union;Peak blood flow velocity of medial femoral circumflex artery;Mean blood flow velocity of medial femoral circumflex artery;	—

Secondary

Measure	Time frame
Peak blood flow velocity of lateral femoral circumflex artery;Mean blood flow velocity of lateral femoral circumflex artery;Femeral head necrosis;	—

Countries

China

Contacts

Public ContactWang Xin

Zhongnan Hospital of Wuhan University

wangxin@znhospital.cn+86 13871529647

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026