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The effect and mechanism of negative pressure wound therapy on the survival rate and scar formation of modified Meek skin graft: a prospective randomized controlled study

The effect and mechanism of negative pressure wound therapy on the survival rate and scar formation of modified Meek skin graft: a prospective randomized controlled study

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000034266
Enrollment
Unknown
Registered
2020-06-30
Start date
2020-07-06
Completion date
Unknown
Last updated
2020-07-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Burns

Interventions

control group:Surgical treatment using modified Meek skin grafting
experimental group:Surgical treatment using negative pressure wound therapy+modified Meek skin grafting

Sponsors

Southwest Hospital, Army Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. The patient's bilateral limbs (upper or lower limbs) are burned simultaneously and all need to be treated with Meek skin grafting (Meek skin graft indication: various wounds requiring autologous skin graft.Including: (1) Early removal of scab and necrotic tissue Fresh granulation wounds. (2) The wounds are not skinned after the first phase of scab removal surgery, and the wounds need to be skinned in the second phase. (3) For granulation wounds without obvious infection, old granulation tissue must be removed before transplantation to form fresh dermal wounds); 2. Those who did not undergo skin graft surgery before admission; 3. Age: >= 18 years old; 4. Patients have no cognitive impairment and can make informed consent on their own; 5. The patient accepted the treatment plan provided by the doctor and accepts bilateral limbs to carry out different surgical methods.

Exclusion criteria

Exclusion criteria: 1. Patients whose donor sites were insufficient to complete bilateral limb skin grafting at the same time; 2. Patients with hemophilia or patients with spontaneous bleeding tendency; 3. Are participating in or have participated in other clinical research related to burns within 6 months.

Design outcomes

Primary

MeasureTime frame
Graft survival rate;Blister growth on postoperative wound surface;Secondary surgery rate;

Secondary

MeasureTime frame
Culture of wound secretions;Crepe stick condition;Scar growth in the Meek skin graft area;

Countries

China

Contacts

Public ContactFei Xiang

Southwest Hospital, Army Medical University

xftmmu@aliyun.com+86 13098777287

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026