Malignant Tumors of the Digestive Tract
Conditions
Interventions
immunotherapy cohort:cytotoxic T lymphocytes transfusion
chemotherapy cohort:modified FOLFOX6 regimens
Sponsors
Yan'an Affiliated Hospital of Kunming Medical University
Eligibility
Sex/Gender
All
Age
16 Years to 82 Years
Inclusion criteria
Inclusion criteria: (1) Aged 18- 85 years; (2) With resectable colorectal tumors confirmed by postoperative histopathology; (3) Patients are required to have a Karnofsky performance score (KPS) of at least 70 before treatment. (3) Patients are required to have adequate hematologic, hepatic, and renal function [hemoglobin >=8 g/dL, platelets >=100,000/uL, white blood cell count >3,000/uL, serum ALT, AST and TBIL <=1.5 ULN, serum blood urea nitrogen <25mg/dL, serum creatinine <1.8 mg/dL].
Exclusion criteria
Exclusion criteria: (1) Accompanied by uncontrolled cardiovascular or pulmonary disease. With liver function failure (ALT, AST, or GGT is 1.5 times higher than the upper limit of normal value, BUN or Cr is beyond the range of normal value). (2) Pregnant (women of childbearing age with positive pregnancy test) or lactating women. (3) Patients with immune system diseases. (4) With a history of alcohol or drug abuse.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Progression-free survival; | — |
Secondary
| Measure | Time frame |
|---|---|
| adverse events; | — |
Countries
China
Contacts
Public ContactRu-Hong Li
Yan'an Affiliated Hospital of Kunming Medical University
Outcome results
None listed