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Cervical cancer-secreted exosomal lncRNA UCA1 promotes lymphangiogenesis by increasing glycolysis

Cervical cancer-secreted exosomal lncRNA UCA1 promotes lymphangiogenesis by increasing glycolysis

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000034241
Enrollment
Unknown
Registered
2020-06-29
Start date
2020-07-01
Completion date
Unknown
Last updated
2020-07-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cervical cancer

Interventions

normal cervical tissue vs. cervical cancer tissue:Nil

Sponsors

Peking Union College of Gynecology and Obstetrics, Tongji Medical College, Huazhong University of Science and Technology
Lead Sponsor

Eligibility

Sex/Gender
Female

Inclusion criteria

Inclusion criteria: Patients with cervical cancer met the inclusion criteria. 1. There were no radiotherapy, chemotherapy and biological targeted therapy before cervical tissue sampling, and all cases were confirmed by pathology; 2. The subjects are not restricted by nationality, race and age; 3. Patients who agree to participate in the trial and sign informed consent, and can be followed up regularly; 4. Patients can provide blood and tumor tissue samples; 5. ECoG score was 0 or 1; 6. Good organ function.

Exclusion criteria

Exclusion criteria: 1. Patients with the following serious complications: heart disease, liver disease, kidney disease, endocrine disease, etc.; 2. Patients with infectious diseases; 2. Patients with undiagnosed abnormal genital tract bleeding; 3. Patients with other tumors; 4. Doctors judge the unsuitable subjects; 5. Patients with history of alcoholism and drug abuse (within 6 months before the trial); 6. The subjects used other experimental drugs within 1 month before the test.

Design outcomes

Primary

MeasureTime frame
cervical tissue;

Countries

China

Contacts

Public ContactWang Hongbo

Peking Union College of Gynecology and Obstetrics, Tongji Medical College, Huazhong University of Science and Technology

hb_wang1969@sina.com+86 13720228749

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026