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Clinical research of using high resolution vessel wall magnetic resonance to evaluate the therapeutic effect of statins in intracranial atherosclerotic stenosis

Clinical and basic research of using high resolution vessel wall magnetic resonance to evaluate the therapeutic effect of statins in intracranial atherosclerotic stenosis

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000034235
Enrollment
Unknown
Registered
2020-06-29
Start date
2019-03-27
Completion date
Unknown
Last updated
2020-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

intracranial atherosclerosis

Interventions

experimental group:Atorvastatin calcium 20mg daily orally

Sponsors

The Fourth Affiliated Hospital of China Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 80 Years

Inclusion criteria

Inclusion criteria: (1) the clinical diagnosis of patients with intracranial atherosclerotic arterial stenosis (should include ultrasound, CT or MRI results); (2) patients taking statins for the first time in treatment of atherosclerotic intracranial artery stenosis; (3) patients aged 20 to 80 years; (4) at least one or more than one of the atherosclerosis risk factors: hypertension, diabetes, hyperlipidemia, smoking, and obesity.

Exclusion criteria

Exclusion criteria: (1) HR MRI contrentions; (2) HRMRI sequences were incomplete or the image quality was poor and could not be measured and analyzed; (3) pregnant women and children.

Design outcomes

Primary

MeasureTime frame
plaque burden of MRI;character of plaque of MRI;stenosis rate of MRI;TG CHOHDLLDL;—

Countries

China

Contacts

Public ContactWu Yejun

Department of Radiology, the Fourth Affiliated Hospital of China Medical University

naych1@163.com+86 13591691080

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026