Anesthesia of Upper gastrointestinal endoscopy
Conditions
Interventions
Cohort 1:iv.remimazolam+sufentanil
Cohort 2:iv.remimazolam+ butorphanol tartrate injection
Cohort 3:iv.propofol+sufentanil
Sponsors
The Second Affiliated Hospital of Hainan Medical University
Eligibility
Sex/Gender
All
Age
60 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. ASA I or II; 2. patients aged 60-80 years, who scheduled to undergo a diagnostic upper gastrointestinal endoscopy; 3. signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Allergic to benzodiazepines and any of the designer ingredients; 2. Myasthenia gravis; 3. Schizophrenia and severe depression; 4. Pathological obesity/obstructive sleep apnea; 5. Acute upper respiratory tract infection; 6. Asthma attack period; Uncontrolled severe hypertension; 7. Unstable angina; 8. Severe liver dysfunction; 9. Acute upper gastrointestinal bleeding with shock; 10. Severe anemia; 11. Gastrointestinal obstruction with gastric content retention; 12. A history of long-term sedative and analgesic medication and allergy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified Observer’s Assessment of Alertness/Sedation;NBP;Heart rate;Breathing rate;SPO2;time of recovery from anesthesia;dosage; | — |
Countries
China
Contacts
Public ContactSun Hu
The Second Affiliated Hospital of Hai'nan Medical University
Outcome results
None listed