liver cancer
Conditions
Interventions
control group:Normal saline
Sponsors
Tianjin Medical University General Hospital
Eligibility
Sex/Gender
All
Age
15 Years to 75 Years
Inclusion criteria
Inclusion criteria: (1) Preoperative diagnosis of liver cancer, no portal vein trunk involvement, no distant metastasis, elective partial hepatectomy; (2) Older than 15 years and younger than 75 years (including 15 and 75 years); (3) Liver and kidney function was basically normal, without obvious complications of heart, lung, kidney and other important organs; liver function was child-A/B grade and ASA grade I-III; (4) Drugs affecting liver function and blood coagulation system were not used before surgery; (5) Pringe method was used in intraoperative golden a hepatic blood flow barrier analysis.
Exclusion criteria
Exclusion criteria: (1) Chronic inflammatory diseases that affect the immune and metabolic system; (2) Abnormal state of coagulation function; (3) Active infection; (4) Intraoperative occlusion of total hepatic blood flow was less than 30 minutes or more than 90 minutes; (5) Other factors, such as drug allergy, are not suitable for the administration of N-acetylcysteine after evaluation by clinicians; (6) Refuse to participate in or quit the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Liver function; | — |
Secondary
| Measure | Time frame |
|---|---|
| Interleukin-6;Tumor necrosis factor;Interleukin-10;Superoxide dismutase;Malondialdehyde;Clinical indicators; | — |
Countries
China
Contacts
Public ContactLiu Quanyan
Tianjin Medical University General Hospital
Outcome results
None listed