patients performing allogeneic stem cell transplantation
Conditions
Interventions
Case series:IL2
Sponsors
Peking University People's Hospital
Eligibility
Sex/Gender
All
Age
15 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Aged 15-65 years old; 2. patients are in complete remission(CR1/CR2) who received haploidentical allo-HSCT; 3. KFS score >=90%; 4. WBC engraftment(ANC>500/ul for continuous 3 days); 5. Patients who have occured III-IV aGVHD; 6. no severe infections; 7. no active II-IV aGVHD and engraftment syndrome; 8. IL-2 intervention should be started within 3 months after transplantation in principle; 9. non T-ALL.
Exclusion criteria
Exclusion criteria: 1. Poor patient compliance; 2. Active II-IV aGVHD; 3. Patients who has serious damage of the heart, lung, liver, kidney and other important organs; 4. Exposure to any other clinical trails prior to enrollment; 5. The researchers considered it inappropriate for patients to participate in observational studies.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Effectiveness: moderate to severe cGVHD; | — |
Countries
China
Contacts
Public ContactXiao-Jun Huang
Peking University People's Hospital
Outcome results
None listed