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Browning of white adipocyte in poorly survived fat grafts in mice and patients

Browning of white adipocyte in poorly survived fat grafts in mice and patients

Status
Active, not recruiting
Phases
Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000034165
Enrollment
Unknown
Registered
2020-06-27
Start date
2019-02-01
Completion date
Unknown
Last updated
2020-06-29

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

fat grafts necrosis

Interventions

1. Breast Cancer
2. Benign breast nodules
3. Breast hyperplasia:Nil
1.Patients undergoing at least one- time autologous fat transfer for breast augmentation, in which post-operative nodule formation were observed on operation zone in 6 months to 1 year after their pri
2. Patients operated with primary breast reconstruction with DIEP flaps and secondary revision surgery:Nil

Sponsors

Breast Plastic Surgery Center, Plastic Surgery Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
22 Years to 58 Years

Inclusion criteria

Inclusion criteria: 1.Patients undergoing at least one- time autologous fat transfer for breast augmentation, in which post-operative nodule formation were observed on operation zone in 6 months to 1 year after their primary surgeries. 2. Patients operated with primary breast reconstruction with DIEP flaps and secondary revision surgery due to minor necrosis in transferred flaps, which occurred in 4 to 6 months after the primary flap transfer. 3.Patients consented to participate in the study.

Exclusion criteria

Exclusion criteria: Patients who had systematic diseases, other diseases, or medication history were excluded from the study.

Design outcomes

Primary

MeasureTime frame
UCP-1;

Countries

China

Contacts

Public ContactJie Luan

Breast Plastic Surgery Center, Plastic Surgery Hospital, Chinese Academy of Medical Sciences, Peking Union Medical College

veratongliu@gmail.com+86 13911701581

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026