Impaired skin barrier function
Conditions
Interventions
1:Apply hand cream to the mouth of the right hand
2:Apply hand cream to your hands after each wash
Sponsors
School of Public Health, Zhengzhou University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Test 1, 2: 1. Choose healthy volunteers from 18 to 25 years old; 2. Volunteers has no common skin diseases, such as contact dermatitis, eczema, urticaria, etc.; 3. Study volunteers with skin moisture content>20A.U, TEWL=15gh/cm2. 4. Research volunteers shall not use any skin care products such as hand cream and face cream 3 days before participating in the experiment. Test 4: 1. Choose healthy volunteers aged 18-79 years; 2. The research volunteers has no common skin diseases, such as contact dermatitis, eczema, urticaria, etc.; 3. Research volunteers shall not use any washing and skin care products at least 3 days before participating in the experiment.
Exclusion criteria
Exclusion criteria: Test 1, 2: 1. Exclude volunteers who cannot conduct the whole experiment; 2. Exclude volunteers with common skin diseases, such as contact dermatitis, eczema, urticaria and other diseases; 3. Exclude volunteers whose skin is sensitive muscles, and exclude subjects whose skin does not meet the water content of 20A.U. and TEWL<=20gh/cm2; 4. Exclude volunteers who smoke or drink alcohol. Test 3: 1. Exclude volunteers who cannot participate in the experiment all the way; 2. Exclude volunteers with common skin diseases, such as contact dermatitis, eczema, urticaria and other diseases; 3. Exclude the research volunteers of daily use of skin care products. Test 4: 1. Exclude volunteers who cannot conduct the whole experiment; 2. Exclude volunteers with common skin diseases, such as contact dermatitis, eczema, urticaria and other diseases.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Skin lipid; | — |
Secondary
| Measure | Time frame |
|---|---|
| Skin surface moisture;Transepidermal water loss value; | — |
Countries
China
Contacts
Public Contactzhenxing Mao
School of Public Health, Zhengzhou University
Outcome results
None listed