Liver cirrhosis
Conditions
Interventions
The treatment group:Facal microbiota transplantation
Sponsors
Mianyang Central Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. The patients who met the diagnostic criteria of ascites due to cirrhosis had no improvement in the condition of the last one who received routine treatment of liver protection, diuresis and nutritional support. 2. Patients who agree to participate in the clinical study and sign the informed consent can receive the follow-up visit, follow-up and specimen collection on time; 3. Patients aged 18-85 years with unlimited gender and follow-up time longer than 3 months; 4. Those patients who are suitable for gastroenteroscopy and FMT.
Exclusion criteria
Exclusion criteria: 1. Pregnant or lactating women; 2. Drug addicts; 3. Suspected or diagnosed patients with a history of alcohol / drug abuse; 4. Patients with a large history of abdominal surgery; 5. Patients with diseases that may cause gastrointestinal function damage. Such as diabetes, thyroid disease, intestinal obstruction, inflammatory bowel disease (IBD), etc; 6. Patients who took antibiotics, non steroidal anti-inflammatory drugs, microecological agents, gastrointestinal motility drugs, acid suppressants and other drugs that affected intestinal flora 2 weeks before treatment; 7. 2 weeks ago, patients with gastrointestinal bleeding or spontaneous bacterial peritonitis (SBP); 8. Patients with other serious diseases that may affect their survival (including serious infection, serious heart, kidney, respiratory, blood, endocrine, neuropsychiatric and other diseases) or with other types of tumors; 9. Patients who have a history of using immunosuppressants or other serious immunodeficiency diseases, such as human acquired immunodeficiency virus (HIV) infection, rheumatic diseases, etc..
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Clinical symptoms;Liver function;ascites;Changes of intestinal flora; | — |
Countries
China
Contacts
Public ContactLi Xiao'an
Mianyang Central Hospital
Outcome results
None listed