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A prospective, single-center, observational study of the effect of chemotherapy on bone health in adult lymphoma patients

A prospective observational study of bone health in patients with lymphoma

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2000034088
Enrollment
Unknown
Registered
2020-06-23
Start date
2020-07-01
Completion date
Unknown
Last updated
2023-06-12

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

lymphoma

Interventions

Case series:NA

Sponsors

The First Affiliated Hospital of Zhejiang University Medical College
Lead Sponsor

Eligibility

Sex/Gender
All
Age
20 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18 to 75 years old patients; 2. Patients with newly diagnosed lymphoma who need to be treated, or patients who need to be treated due to the recent disease progress without treatment due to previous disease assessment; 3. Patients who need at least 4 courses of single or combined chemotherapy; 4. Patients who can be treated with rituximab or single drug of small molecule kinase inhibitor, with or without radiotherapy.

Exclusion criteria

Exclusion criteria: 1. Patients with known history of osteoporosis or osteoporotic fracture caused by bone metabolism disease; 2. Patients who have been or are diagnosed with other malignant tumors except lymphoma; 3. Patients with controlled and / or uncontrolled endocrine problems (primary or secondary hyperparathyroidism), metabolic bone disease (Paget disease); 4. The clearance rate of creatinine is less than 60 ml / min, which is considered to be caused by lymphoma and can be accepted by patients who recover after treatment; 5. Patients with a long history of glucocorticoid therapy; 6. Patients with previous history of lumbar radiotherapy; 7. Patients with lymphoma involving lumbar or hip joint.

Design outcomes

Primary

MeasureTime frame
Bone density;Bone metabolism related factors;

Countries

China

Contacts

Public ContactJingsong He

The First Affiliated Hospital of Zhejiang University Medical College

hejingsong@zju.edu.cn+86 13600547247

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026