lymphoma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 18 to 75 years old patients; 2. Patients with newly diagnosed lymphoma who need to be treated, or patients who need to be treated due to the recent disease progress without treatment due to previous disease assessment; 3. Patients who need at least 4 courses of single or combined chemotherapy; 4. Patients who can be treated with rituximab or single drug of small molecule kinase inhibitor, with or without radiotherapy.
Exclusion criteria
Exclusion criteria: 1. Patients with known history of osteoporosis or osteoporotic fracture caused by bone metabolism disease; 2. Patients who have been or are diagnosed with other malignant tumors except lymphoma; 3. Patients with controlled and / or uncontrolled endocrine problems (primary or secondary hyperparathyroidism), metabolic bone disease (Paget disease); 4. The clearance rate of creatinine is less than 60 ml / min, which is considered to be caused by lymphoma and can be accepted by patients who recover after treatment; 5. Patients with a long history of glucocorticoid therapy; 6. Patients with previous history of lumbar radiotherapy; 7. Patients with lymphoma involving lumbar or hip joint.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bone density;Bone metabolism related factors; | — |
Countries
China
Contacts
The First Affiliated Hospital of Zhejiang University Medical College