head and neck cancer
Conditions
Interventions
A group :Goal-directed Fluid therapy
B group :traditional Fluid therpy
Sponsors
The second Xiangya Hospital of Central South University
Eligibility
Sex/Gender
All
Age
65 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 65-85 years (including boundary value); 2. Patients whose operation time is more than 6 hours; 3. ASA class I-III patients; 4. Patients with BMI between 18-30 (including boundary value); 5. Patients who voluntarily sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with acute kidney disease or acute renal insufficiency; 2. Dialysis patients; 3. Diabetic patients; 4. Patients allergic to hydroxyethyl starch; 5. Patients with obvious arrhythmia and cardiac insufficiency; 6. Patients with edema, pleural effusion and ascites; 7. Patients with abnormal thyroid function; 8. Patients who used trimethoprim and cimetidine in the past 3 months; 9. Patients who used hormone in the past 3 months; 10. Patients considered unsuitable for this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| the function of free flap;postoperative complications ;The length of stay; | — |
Secondary
| Measure | Time frame |
|---|---|
| Urine Routine Examination;Urine volume;Intraoperative infusion volume ;LAC (arterial blood gas analysis);Blood transfusion volume ;MAP (mean arterial pressure);SVV (stroke volume variation);cardiovascular events ; | — |
Countries
China
Contacts
Public ContactXu Junmei
Department of Anesthesiology, the Second Xiangya Hospital of Central South University
Outcome results
None listed