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the effectiveness and safty of sodium bicarbonate Ringer's solution in perioperative fluid therapy for patients with one lung ventilation

the effectiveness and safty of sodium bicarbonate Ringer's solution in perioperative fluid therapy for patients with one lung ventilation

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2000034053
Enrollment
Unknown
Registered
2020-06-22
Start date
2020-07-01
Completion date
Unknown
Last updated
2020-06-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Resipiratory and intrathoracic organs, personal history of other malignant tumors

Interventions

Group B:input BRS
Group L:input LRS

Sponsors

the Second Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 99 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing elective thoracoscopic surgery, during which patients are expected to have one lung ventilation time >1h and 18 years old, ASA I-III grade; 3. After fully explaining the contents of the clinical trial, those who voluntarily joined and signed the informed consent.

Exclusion criteria

Exclusion criteria: 1. Chest surgery for artificial pneumothorax or thoracotomy; 2. Patients with severe pulmonary hypertension, arrhythmia or cardiac insufficiency; 3. Patients with renal dysfunction (Cre: 2 mg/dL or more or BUN: 40 mg/dL or more); 4. Patients with hypothyroidism; 5. Patients with past allergies; 6. Patients during pregnancy or lactation; 7. Patients with severe anemia with hemoglobin below 7.0g/dl, or donated blood within the last 3 months (except for blood drawn for self-blood transfusion) (when consent is obtained); 8. Patients who participated in other treatments in the last 6 months (when consent was obtained); 9. Patients judged as lack of consent; 10. Other patients who are judged as inappropriate by the clinically responsible doctor or clinical supervisor.

Design outcomes

Primary

MeasureTime frame
Arterial carbon dioxide partial pressure;Alkali surplus;

Secondary

MeasureTime frame
Lactic acid;Blood electrolyte;Hemodynamic parameters;Hemodynamic parameters;Hemodynamic parameters;

Countries

China

Contacts

Public ContactZhang Ye

the Second Affiliated Hospital of Anhui Medical University

zhangye_hassan@sina.com+86 13966768081

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026