POD
Conditions
Interventions
Group A: BIS monitoring group:Group A: adjust the anesthesia depth according to the BIS value, mainly by adjusting the infusion speed of propofol anesthesia drugs to maintain the BIS value within the
rSO2 monitoring group (group B):Group B: anesthesia management was carried out according to the cerebral oxygen saturation value, and the range of rSO2 was maintained at 60% - 70%. If the absolute val
Monitoring group of bis combined with rSO2 (Group C):Combined with BIS and cerebral oxygen saturation monitoring, the BIS value is kept within the target range of 50-60, and the rSO2 is kept within th
Sponsors
The Second Affiliated Hospital of Anhui Medical University
Eligibility
Sex/Gender
All
Age
65 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1. Gender unlimited, age 65-85, ASA II or III; 2. Those patients who did not take psychoactive drugs within half a year before admission; 3. Patients without hepatorenal dysfunction; 4. Patients with normal temperature before operation; 5. Patients who can correctly understand the score of MMSE are excluded from those who can not cooperate with the score measurement and are lower than the lowest score of corresponding education level (illiteracy <=17 points, primary school <=20 points, middle school <=22 points, University <=23 points).
Exclusion criteria
Exclusion criteria: 1. Patients with central nervous system diseases take sedatives and antidepressants; 2. Patients with severe cerebrovascular disease, cerebral metabolic disease, dementia history, etc., who have been drinking for a long time; 3. Patients with severe organ dysfunction; 4. Patients with severe visual, auditory or language communication disorders; 5. Patients with preoperative MMSE score < 23.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| MMSE score;CAM-CR score;VAS score; | — |
Countries
China
Contacts
Public ContactHu Xianwen
The Second Affiliated Hospital of Anhui Medical University
Outcome results
None listed